Neuroprotective Effect of E3 Ubiquitin Ligase RNF8 Against Ischemic Stroke via HDAC2 Stability Reduction and Reelin-Dependent GSK3β Inhibition
Xiaoxi Zhu, Jun‐Xiang Li, Dengwei You, Yan Xiao, Zhi Huang, Wenfeng Yu
Topics & Concepts
NeuroprotectionUbiquitin ligaseGSK3BGSK-3Downregulation and upregulationUbiquitinOxidative stressReelinPharmacologyChemistryCell biologyBiologyKinaseBiochemistryExtracellular matrixGeneHistone Deacetylase Inhibitors ResearchNuclear Receptors and SignalingMoyamoya disease diagnosis and treatment