A NIR-triggered multifunctional nanoplatform mediated by Hsp70 siRNA for chemo-hypothermal photothermal synergistic therapy
Bo Zhang, Chenwen Shao, Kang-Min Zhou, Qin Li, Yongtao Duan, Yu‐Shun Yang, Hai‐Liang Zhu
Abstract
photothermal effect as well as the anti-tumor activity, we found that the added Hsp-70 siRNA enhanced the synergistic anti-cancer activity of HPTT and chemotherapy. In summary, this work holds great potential in cancer treatment, and suggests better efficacy of synergistic chemo/HPTT than the single-agent therapy.
Topics & Concepts
Photothermal therapyCancer therapyChemistryCombination therapyCancer researchCancerNanotechnologyMedicinePharmacologyMaterials scienceInternal medicineNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryRNA Interference and Gene Delivery