When MARCH family proteins meet viral infections
Chunfu Zheng, Yan‐Dong Tang
Abstract
Membrane-associated RING-CH (MARCH) ubiquitin ligases belong to a RING finger domain E3 ligases family. Recent studies have demonstrated that MARCH proteins play critical roles during various viral infections. MARCH proteins can directly antagonize different steps of the viral life cycle and promote individual viral infection. This mini-review will focus on the latest advances of MARCH family proteins' emerging roles during viral infections.
Topics & Concepts
BiologyUbiquitinViral infectionVirologyViral proteinComputational biologyGeneticsVirusGeneinterferon and immune responsesCancer-related Molecular PathwaysCell death mechanisms and regulation