Novel copper(<scp>ii</scp>) complexes with fenamates and isonicotinamide: structure and properties, and interactions with DNA and serum albumin
Flóra Jozefíková, Spyros Perontsis, Miriama Šimunková, Zuzana Barbieriková, Ĺubomíŕ́ Švorc, Marián Valko, George Psomas, Ján Moncóľ
Abstract
Reactions of non-steroidal anti-inflammatory drugs tolfenamic, meclofenamic, mefenamic, clonixic and niflumic acids with isonicotinamide and copper(<sc>ii</sc>) acetate resulted in the formation of five novel mixed-ligand Cu(<sc>ii</sc>) coordination compounds.
Topics & Concepts
ChemistryIsonicotinamideCopperDNAAlbuminBovine serum albuminPolymer chemistryBiophysicsBiochemistryOrganic chemistryHydrogen bondMoleculeBiologyMetal complexes synthesis and propertiesCrystal structures of chemical compoundsOrganometallic Compounds Synthesis and Characterization