Biosynthesis of triacsin featuring an N-hydroxytriazene pharmacophore
Antonio Del Rio Flores, Frederick F. Twigg, Yongle Du, Wenlong Cai, Daniel Q. Aguirre, Michio Sato, Moriel J. Dror, Maanasa Narayanamoorthy, Jiaxin Geng, Nicholas A. Zill, Rui Zhai, Wenjun Zhang
Topics & Concepts
MoietyPharmacophoreBiosynthesisEnzymeChemistryBiochemistryStereochemistryGlycineMutagenesisHydrazine (antidepressant)Combinatorial chemistryAmino acidGeneMutationMicrobial Natural Products and BiosynthesisEnzyme Catalysis and ImmobilizationChemical synthesis and alkaloids