Litcius/Paper detail

Biocatalysts Based on Peptide and Peptide Conjugate Nanostructures

Ian W. Hamley

2021Biomacromolecules80 citationsDOIOpen Access PDF

Abstract

design (minimalist approach) of effective catalytic structures that mimic the binding pockets of natural enzymes or which simply present catalytic motifs at high density on nanostructure scaffolds. Research on these topics is summarized, along with a discussion of metal nanoparticle catalysts templated by peptide nanostructures, especially fibrils. Research showing the high activities of different classes of peptides in catalyzing many reactions is highlighted. Advances in peptide design and synthesis methods mean they hold great potential for future developments of effective bioinspired and biocompatible catalysts.

Topics & Concepts

PeptideChemistryBiocatalysisCombinatorial chemistryCatalysisAldol reactionNanostructureArtificial enzymeNanotechnologyMaterials scienceOrganic chemistryBiochemistryReaction mechanismChemical Synthesis and AnalysisSupramolecular Self-Assembly in MaterialsAntimicrobial Peptides and Activities