Litcius/Paper detail

The nervous system during <scp>COVID</scp>‐19: Caught in the crossfire

Nick R. Natale, John R. Lukens, William A. Petri

2022Immunological Reviews16 citationsDOIOpen Access PDF

Abstract

SARS-CoV-2, the virus that causes coronavirus disease (COVID)-19, has become a persistent global health threat. Individuals who are symptomatic for COVID-19 frequently exhibit respiratory illness, which is often accompanied by neurological symptoms of anosmia and fatigue. Mounting clinical data also indicate that many COVID-19 patients display long-term neurological disorders postinfection such as cognitive decline, which emphasizes the need to further elucidate the effects of COVID-19 on the central nervous system. In this review article, we summarize an emerging body of literature describing the impact of SARS-CoV-2 infection on central nervous system (CNS) health and highlight important areas of future investigation.

Topics & Concepts

AnosmiaCentral nervous systemCoronavirus disease 2019 (COVID-19)CoronavirusNervous systemSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Disease2019-20 coronavirus outbreakImmunologyVirusMedicineNeuroscienceBiologyVirologyPathologyInfectious disease (medical specialty)OutbreakLong-Term Effects of COVID-19Olfactory and Sensory Function StudiesCOVID-19 Clinical Research Studies