Mitochondrial dysfunction and apoptosis underlie the hepatotoxicity of perhexiline
Zhen Ren, Si Chen, Ji‐Eun Seo, Xiaoqing Guo, Dongying Li, Baitang Ning, Lei Guo
Topics & Concepts
Mitochondrial permeability transition poreApoptosisCytotoxicityPharmacologyMitochondrionCaspase 3CaspaseProgrammed cell deathBlotChemistryBiologyBiochemistryIn vitroGenePharmacogenetics and Drug MetabolismPharmacological Effects of Natural CompoundsDrug-Induced Hepatotoxicity and Protection