Canthin-6-one (CO) from Picrasma quassioides (D.Don) Benn. ameliorates lipopolysaccharide (LPS)-induced astrocyte activation and associated brain endothelial disruption
Qian Yue, Yunshao Xu, Ligen Lin, Maggie Pui Man Hoi
Topics & Concepts
Proinflammatory cytokineAstrocyteNeuroinflammationBlood–brain barrierChemistryLipopolysaccharideNitric oxideNitric oxide synthaseMicrogliaPharmacologyTumor necrosis factor alphaBlotCell biologyNeuroprotectionImmunologyInflammationBiologyBiochemistryCentral nervous systemEndocrinologyOrganic chemistryGenePhytochemical compounds biological activitiesStudies on Chitinases and ChitosanasesSeaweed-derived Bioactive Compounds