Nanoparticles‐Mediated CRISPR/Cas Gene Editing Delivery System
Phei Er Saw, Guohui Cui, Xiaoding Xu
Abstract
CRISPR/Cas system has become one of the most powerful techologies in biomedical research, and has showed great potentials in the gene related diseases. However, efficient delivery systems of CRISPR/Cas to target cells remains challenging. In recent years, nanoparticles have showned great potentials for the delivery of CRISPR/Cas systems. This paper mainly approaches the development and new strategies of CRISPR/Cas delivery systems, as well as their application in the clinical diseases. By summarizing the CRISPR/Cas systems delivery, new strategies are expected for the gene therapy.
Topics & Concepts
CRISPRGene deliveryGenome editingComputational biologyDelivery systemGeneNanotechnologyGenetic enhancementComputer scienceBiologyGeneticsMaterials sciencePharmacologyCRISPR and Genetic EngineeringRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques