Hyperosmolarity promotes macrophage pyroptosis by driving the glycolytic reprogramming of corneal epithelial cells in dry eye disease
Yu Han, Yu Alex Zhang, Kelan Yuan, Yaying Wu, Xiuming Jin, Xiaodan Huang
Topics & Concepts
PyroptosisReprogrammingCell biologyInflammationGlycolysisIn vivoMacrophageDownregulation and upregulationInduced pluripotent stem cellBiologyChemistryImmunologyIn vitroCellInflammasomeBiochemistryMetabolismGeneBiotechnologyEmbryonic stem cellOcular Surface and Contact LensCorneal Surgery and TreatmentsAdvanced Glycation End Products research