Litcius/Paper detail

Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors

Xiaohan Song, Pu Sun, Jiang Wang, Wei Guo, Yi Wang, Linghua Meng, Hong Liu

2020European Journal of Medicinal Chemistry33 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryIndoleamine 2,3-dioxygenasePotencyPharmacokineticsBioavailabilityIC50PharmacologyEnzymeOxadiazoleIn vivoStereochemistryIn vitroBiochemistryTryptophanAmino acidMedicineOrganic chemistryBiotechnologyBiologyTryptophan and brain disordersBipolar Disorder and TreatmentPharmacological Receptor Mechanisms and Effects