Nanocurcumin: preparation, characterization and cytotoxic effects towards human laryngeal cancer cells
Demiana H. Hanna, Gamal R. Saad
Abstract
The aim of this study was to prepare curcumin nanoparticles using a sol–oil method to improve curcumin absorption and bioavailability, and to investigate the therapeutic effect of the prepared nanoparticles on the inhibition mechanisms toward human Hep-2 cancer cells.
Topics & Concepts
CurcuminApoptosisChemistryFlow cytometryHep G2Cytotoxic T cellCell cycleCancer cellIC50Growth inhibitionDownregulation and upregulationMolecular biologyBiochemistryBiophysicsIn vitroBiologyCancerMedicineInternal medicineGeneCurcumin's Biomedical ApplicationsRNA Interference and Gene DeliveryCell death mechanisms and regulation