Vitamin-B12-conjugated PLGA-PEG nanoparticles incorporating miR-532-3p induce mitochondrial damage by targeting apoptosis repressor with caspase recruitment domain (ARC) on CD320-overexpressed gastric cancer
Zhian Chen, Yanrui Liang, Xiaoli Feng, Liang Yu, Guodong Shen, Huilin Huang, Zhaoyu Chen, Jiang Yu, Hao Liu, Lin Tian, Hao Chen, Dong Wu, Guoxin Li, Bingxia Zhao, Weihong Guo, Yanfeng Hu
Topics & Concepts
ApoptosisCytochrome cMitochondrionMitochondrial permeability transition poreChemistryCell biologyCancer cellMolecular biologyBiologyBiochemistryProgrammed cell deathCancerGeneticsRNA Interference and Gene DeliveryMicroRNA in disease regulationAdvanced biosensing and bioanalysis techniques