Lipid nanoparticles fuse with cell membranes of immune cells at low temperatures leading to the loss of transfection activity
Takashi Nakamura, Koharu Yamada, Yusuke Sato, Hideyoshi Harashima
Topics & Concepts
Jurkat cellsTransfectionImmune systemInternalizationCell biologyCellViral envelopeCell cultureGene silencingChemistrySmall interfering RNAT cellBiologyVirusBiochemistryVirologyImmunologyGeneGeneticsRNA Interference and Gene DeliveryVirus-based gene therapy researchImmune Cell Function and Interaction