<p>First Report of OXA-181-Producing <em>Klebsiella pneumoniae</em> in China</p>
Congcong Liu, Yinfei Fang, Yu Zeng, Jiayue Lu, Qiaoling Sun, Hongwei Zhou, Zhangqi Shen, Gongxiang Chen
Abstract
Abstract: We present here the first report of an OXA-181-producing Klebsiella pneumoniae isolated from the fecal specimen of a patient in China. The OXA-181-encoding gene bla OXA-181 was located on a 51 kb IncX3-type plasmid. Conjugation assay and whole-genome sequencing analysis revealed that this transferrable plasmid in the K. pneumoniae isolate might have originated from Escherichia coli and have the potential to mediate the spread of bla OXA-181 . Keywords: OXA-181, Klebsiella pneumoniae , IncX3 plasmid, China, human
Topics & Concepts
Klebsiella pneumoniaePlasmidEscherichia coliMicrobiologyGeneBiologyEnterobacteriaceaeGeneticsAntibiotic Resistance in BacteriaGenomics and Phylogenetic StudiesBacterial Genetics and Biotechnology