Mitochondrial Contact Site and Cristae Organization System and F <sub>1</sub> F <sub>O</sub> -ATP Synthase Crosstalk Is a Fundamental Property of Mitochondrial Cristae
Lawrence Rudy Cadena, Ondřej Gahura, Brian Panicucci, Alena Zı́ková, Hassan Hashimi
Abstract
, just as in baker's yeast. This is remarkable considering that these complexes have otherwise undergone many changes during their almost 2 billion years of independent evolution. Thus, this crosstalk is a fundamental property needed to maintain proper mitochondrial structure even if the constituent players considerably diverged.
Topics & Concepts
ATP synthaseCristaATP synthase gamma subunitProtein subunitMitochondrionCrosstalkChemiosmosisBiologyCell biologyV-ATPaseATPaseChemistryBiochemistryATP hydrolysisEnzymeGenePhysicsOpticsMitochondrial Function and PathologyATP Synthase and ATPases ResearchMetalloenzymes and iron-sulfur proteins