Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors
Zhi‐Xin Lei, Haowei Meng, Zhicong Lv, Menghao Liu, Huanan Zhao, Hao Wu, Xiaoxue Zhang, Lulu Liu, Yuan Zhuang, Kailin Yin, Yongchang Yan, Chengqi Yi
Topics & Concepts
CRISPRGenome editingCas9Computational biologyCytosineBiologyPoint mutationSequence (biology)DNAGenomeGeneticsMutationGeneCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsRNA regulation and disease