Brunner’s Gland Hamartoma of the Duodenum: A Literature Review
Menghua Zhu, Hongyu Li, Yanyan Wu, Yang An, Yuye Wang, Ye Chun, Dan Zhang, Rui Ma, Xuehan Wang, Xiaodong Shao, Xiaozhong Guo, Xingshun Qi
Abstract
Brunner's gland hamartoma is a benign tumor of the duodenum, but has malignant potential with a very low risk of progression into adenocarcinoma. It is uncommon with a frequency of less than 1.0% among the primary tumors of the small intestine. In addition, its clinical manifestations are nonspecific, etiology remains unclear, and treatment strategy needs to be further refined. This literature review mainly discusses the epidemiology, clinical features, possible etiology and pathogenesis, diagnostic methods, malignant potential, treatment, and prognosis of Brunner's gland hamartoma.
Topics & Concepts
MedicineDuodenumHamartomaEtiologyAdenocarcinomaPathologyPathogenesisEpidemiologyInternal medicineGastroenterologyCancerGastrointestinal Tumor Research and TreatmentGastrointestinal disorders and treatmentsNeuroendocrine Tumor Research Advances