Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation
Hun-Goo Lee, Sachiko Imaichi, Elizabeth B. Kraeutler, Rodrigo Aguilar, Yong‐Woo Lee, Steven D. Sheridan, Jeannie T. Lee
Topics & Concepts
FMR1BiologyFragile X syndromeTrinucleotide repeat expansionEpigeneticsDNA demethylationGeneticsGene silencingDNA repairCell biologyGeneDNA methylationFragile xAlleleGene expressionGenetics and Neurodevelopmental DisordersGenomics and Chromatin DynamicsChromosomal and Genetic Variations