Increasing the diversity of nylonases for poly(ester amide) degradation
Jan de Witt, Maike-Elisa Ostheller, Kenneth Jensen, Christian A. M. R. van Slagmaat, Tino Polen, Gunnar Henrik Seide, Stephan Thies, Benedikt Wynands, Nick Wierckx
Abstract
This study extents the sequence space of 6-aminohexanoate endohydrolases (NylC) for future enzyme engineering strategies to boost their nylonase activities, while in parallel novel polymers were designed to align biodegradability and performance.
Topics & Concepts
Degradation (telecommunications)AmideChemistryPolymer chemistryDiversity (politics)Organic chemistryComputer scienceAnthropologySociologyTelecommunicationsbiodegradable polymer synthesis and propertiesBiopolymer Synthesis and ApplicationsClick Chemistry and Applications