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An Engineered Probiotic Produces a Type III Interferon IFNL1 and Reduces Inflammations in <i>in vitro</i> Inflammatory Bowel Disease Models

Koon Jiew Chua, Hua Ling, In Young Hwang, Hui Ling Lee, John C. March, Yung Seng Lee, Matthew Wook Chang

2022ACS Biomaterials Science & Engineering29 citationsDOIOpen Access PDF

Abstract

IBD models, demonstrating their potential as live biotherapeutics for IBD immunotherapy.

Topics & Concepts

Inflammatory bowel diseaseInflammationFOXP3ImmunologyCytokineInterferonProinflammatory cytokineProbioticBiologyMedicineImmune systemDiseasePathologyGeneticsBacteriaInflammatory Bowel DiseaseGut microbiota and healthImmune cells in cancer