High-resolution low-cost LCD 3D printing for microfluidics and organ-on-a-chip devices
Houda Shafique, Vahid Karamzadeh, Geunyong Kim, Molly L. Shen, Yonatan Morocz, Ahmad Sohrabi Kashani, David Juncker
Abstract
, CV: 6.8%). We made PLInk-based organ-on-a-chip devices in 384-well plate format and produced 3420 individual devices within an 8 h print run. We used the devices to co-culture two spheroids separated by a vascular barrier over 5 days and observed endothelial sprouting, cellular reorganization, and migration. LCD 3D printing together with tailored inks pave the way for democratizing access to high-resolution manufacturing of ready-to-use microfluidic and organ-on-a-chip devices by anyone, anywhere.
Topics & Concepts
Microfluidics3D printingLiquid-crystal displayFabricationPhotopolymerNanotechnologyChipMicrofluidic chipThroughputOrgan-on-a-chipHigh resolutionMaterials scienceComputer hardwareComputer scienceOptoelectronicsPolymerTelecommunicationsAlternative medicineWirelessComposite materialPathologyRemote sensingMedicineGeologyPolymerization3D Printing in Biomedical ResearchInnovative Microfluidic and Catalytic Techniques InnovationAdditive Manufacturing and 3D Printing Technologies