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Advanced Nanoformulations for Detection and Removal of Poly- and Perfluoroalkyl Substances (PFAS)

Jyotish Kumar, Mahesh Narayan

2025Pollutants8 citationsDOIOpen Access PDF

Abstract

Perfluoroalkyl substances (PFAS), also known as “forever chemicals”, are a class of highly stable chemical compounds that slowly contaminate waterbodies and soil. The widespread presence of PFAS is associated with adverse human health effects and is a major environmental concern. The conventional, highly sensitive methods used for PFAS detection are LC-MS/MS and solid phase extraction, but they are very complex and expensive. Therefore, there is an urgent need for sensitive, low-cost, and fast methods for the detection and removal of PFAS compounds from water and soil resources. The advancement of nanotechnology has significantly impacted advanced disease diagnosis and treatment in the last few decades. Currently, these engineered nanomaterials (ENMs) have been exploited for the development of advanced nano-enabled techniques for the detection and removal of environmental pollutants. Nano-enabled techniques also offer improved performance over conventional methods. In this review, the details of the detection and removal of PFAS, as well as their optimization and limitations, and future perspectives are discussed. We focused on the implementation of nanomaterials such as nanoparticles, nanotubes, nanorods, and nano*filtration membranes for efficient PFAS detection and removal. We also included the recent literature and global guidelines for PFAS use and the effect of PFAS exposure on human health.

Topics & Concepts

ChemistryEnvironmental chemistryChromatographyPer- and polyfluoroalkyl substances researchToxic Organic Pollutants ImpactAir Quality and Health Impacts
Advanced Nanoformulations for Detection and Removal of Poly- and Perfluoroalkyl Substances (PFAS) | Litcius