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Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation

Mohamed S. Abdel-Hakeem, Sasikanth Manne, Jean‐Christophe Beltra, Erietta Stelekati, Zeyu Chen, Kito Nzingha, Mohammed-Alkhatim Ali, John L. Johnson, Josephine R. Giles, Divij Mathew, Allison R. Greenplate, Golnaz Vahedi, E. John Wherry

2021Nature Immunology243 citationsDOIOpen Access PDF

Topics & Concepts

EpigeneticsStimulationAntigenImmunologyBiologyMedicineCell biologyNeuroscienceGeneticsGeneImmunotherapy and Immune ResponsesImmune Cell Function and InteractionT-cell and B-cell Immunology
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation | Litcius