Nanoscale metal–organic frameworks for the intracellular delivery of CRISPR/Cas9 genome editing machinery
Qizhen Zheng, Wenting Li, Lanqun Mao, Ming Wang
Abstract
The discovery of CRISPR/Cas9 genome-editing technology enables the precise manipulation of mammalian DNA sequences for treating genetic disorders.
Topics & Concepts
CRISPRGenome editingCas9Nanoscopic scaleIntracellularNanotechnologyComputational biologyGenomeChemistryBiologyMaterials scienceGeneBiochemistryCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesAdvanced Nanomaterials in Catalysis