DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway
Rongbo Wen, Leqi Zhou, Siyuan Jiang, Hao Fan, Kuo Zheng, Yue Yu, Xianhua Gao, Liqiang Hao, Zheng Lou, Guanyu Yu, Yang Fu, Wei Zhang
Topics & Concepts
MedicineColorectal cancerWnt signaling pathwayRadiation therapyCancer researchMouse model of colorectal and intestinal cancerIn vivoMethylationCancerOncologyNeoadjuvant therapyInternal medicineSignal transductionBreast cancerBiologyGeneBiochemistryBiotechnologyWnt/β-catenin signaling in development and cancerEpigenetics and DNA MethylationCancer Cells and Metastasis