Visible Light‐Mediated Manipulation of 1,<i>n</i>‐Enynes in Organic Synthesis
Roshan I. Patel, Jitender Singh, Anuj Sharma
Abstract
Abstract The 1, n ‐enynes are potent scaffolds in organic synthesis, providing a state‐of‐the‐art approach for synthesizing various acyclic and carbo‐ and heterocyclic compounds. Radical cascade cyclization and C−H functionalization of 1, n ‐enynes have gained immense attention in the synthetic community. Significant advancement in this field has been developed over the years, employing harsh and expensive metal catalysts usually associated with intense product purification and unwanted side‐products. In this context, the advent of visible light photocatalysis as a mild and efficient approach in the area of 1, n ‐enynes is a welcome step. Herein, we provide an exclusive overview of the recent developments in visible light‐assisted manipulation of 1, n ‐enynes. We have classified the review into 1,3‐, 1,4‐, 1,5‐, 1,6‐, 1,7‐, and 1,8‐enynes, as well as dienyne, and enediyne‐based reactions.