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Construction of chiral chroman skeletons <i>via</i> catalytic asymmetric [4 + 2] cyclization of <i>ortho</i>-hydroxyphenyl-substituted <i>para</i>-quinone methides catalyzed by a chiral-at-metal rhodium complex

Jian Yang, Siliang Ming, Gang Yao, Haifeng Yu, Yu Du, Jun Gong

2022Organic Chemistry Frontiers19 citationsDOI

Abstract

Construction of chiral chroman skeletons via catalytic asymmetric [4 + 2] cyclization of ortho -hydroxyphenyl-substituted p -QMs catalyzed by a chiral-at-metal rhodium complex.

Topics & Concepts

ChemistryRhodiumCatalysisMetalQuinoneEnantioselective synthesisOrganic chemistryCombinatorial chemistrySynthesis of Indole DerivativesAxial and Atropisomeric Chirality SynthesisCatalytic C–H Functionalization Methods
Construction of chiral chroman skeletons <i>via</i> catalytic asymmetric [4 + 2] cyclization of <i>ortho</i>-hydroxyphenyl-substituted <i>para</i>-quinone methides catalyzed by a chiral-at-metal rhodium complex | Litcius