Melanoidins, extracted from Chinese traditional vinegar powder, inhibit alcohol-induced inflammation and oxidative stress in macrophages <i>via</i> activation of SIRT1 and SIRT3
Yang Li, Xin Jia, Ning Tang, Huiyuan Tao, Rong Xia, Yongqiang Cheng
Abstract
Study of the role of melanoidins, extracted from Chinese traditional vinegar powder, in the regulation of alcohol-induced inflammation and oxidative stress using a RAW 264.7 macrophage model, and elucidation of the underlying mechanisms of action.
Topics & Concepts
SIRT3Oxidative stressInflammationChemistrySirtuinAlcoholOxidative phosphorylationTraditional medicineFood sciencePharmacologyBiochemistryBiologyMedicineAcetylationImmunologyGeneSirtuins and Resveratrol in MedicineBiochemical effects in animalsGenomics, phytochemicals, and oxidative stress