Solution structure of deglycosylated human IgG1 shows the role of CH2 glycans in its conformation
Valentina A. Spiteri, James Doutch, Robert P. Rambo, Jayesh Gor, Paul A. Dalby, Stephen J. Perkins
Topics & Concepts
ChemistryRadius of gyrationGlycanFragment crystallizable regionPeptideGlycosylationImmunoglobulin Fc FragmentsImmunoglobulin Fab FragmentsImmunoglobulin GCrystallographyAntibodyBiochemistryPeptide sequenceGlycoproteinComplementarity determining regionBiologyImmunologyReceptorGeneOrganic chemistryPolymerGlycosylation and Glycoproteins ResearchMonoclonal and Polyclonal Antibodies ResearchProtein purification and stability