High-throughput and label-free enrichment of malignant tumor cells and clusters from pleural and peritoneal effusions using inertial microfluidics
Zhixian Zhu, Shuang Li, Dan Wu, Hui Ren, Chen Ni, Cailian Wang, Nan Xiang, Zhonghua Ni
Abstract
. Finally, we performed the rapid drug sensitivity test by coupling the microfluidic enrichment with CCK-8 assay. Our approach may serve as valuable assistance to accelerate cancer diagnosis and guide the selection of treatment medications.
Topics & Concepts
Peritoneal EffusionMalignant pleural effusionPleural effusionCancer researchMedicineBiomedical engineeringMicrofluidicsPathologyMaterials scienceEffusionInternal medicineNanotechnologySurgeryMicrofluidic and Bio-sensing Technologies3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications