Litcius/Paper detail

TFEB protein expression is reduced in aged brains and its overexpression mitigates senescence-associated biomarkers and memory deficits in mice

Hongjie Wang, Mohan Kumar Muthu Karuppan, Dinesh Devadoss, Madhavan Nair, Hitendra S. Chand, Madepalli K. Lakshmana

2021Neurobiology of Aging35 citationsDOI

Topics & Concepts

TFEBSenescenceGenetically modified mouseBiologyHippocampusCell biologyAutophagyNeuroscienceEctopic expressionTransgeneApoptosisGeneticsGeneTelomeres, Telomerase, and SenescenceEpigenetics and DNA MethylationGenomics and Chromatin Dynamics