Litcius/Paper detail

Combination therapy with B7H3-redirected bispecific antibody and Sorafenib elicits enhanced synergistic antitumor efficacy

Cheng Huang, Hongjian Li, Yunyu Feng, Xiaoling Li, Zongliang Zhang, Caiying Jiang, Jichao Wang, Yang Chen-li, Yuying Fu, Min Mu, Shasha Zhao, Zeng Wang, Yi Kuang, Huan Hou, Yuelong Wang, Wenhao Guo, Jianguo Xu, Hui Yang, Liangxue Zhou, Aiping Tong, Gang Guo

2020Theranostics21 citationsDOIOpen Access PDF

Abstract

Overall, our study indicates that combination therapy with sorafenib and B7H3×CD3 BiTE may be a new therapeutic option for the further study of preclinical treatment of OC.

Topics & Concepts

Bispecific antibodySorafenibAntibodyMedicineCancer researchAntibody therapyPharmacologyMonoclonal antibodyChemistryImmunologyHepatocellular carcinomaNanoparticle-Based Drug DeliveryPeptidase Inhibition and AnalysisCancer Research and Treatments