Treatment of COVID-19: a review of current and prospective pharmacotherapies
Eleanor Quek, Hasan Tahir, Poornima Kumar, Robert Hastings, Rajeev Jha
Abstract
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and have grave health and socioeconomic consequences worldwide. Researchers have raced to understand the pathophysiological mechanisms underpinning the disease caused by SARS-CoV-2 so that effective therapeutic targets can be discovered. This review summarises the key pharmacotherapies that are being investigated for treatment of COVID-19, including antiviral, immunomodulator and anticoagulation strategies.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pandemic2019-20 coronavirus outbreakIntensive care medicineCoronavirusDiseaseBetacoronavirusCoronavirus InfectionsPathophysiologyMEDLINEVirologyInternal medicineInfectious disease (medical specialty)OutbreakPolitical scienceLawCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19