Effects of an isatin derivative on tumor cell migration and angiogenesis
Yunsong Chang, Yuan Yuan, Qian Zhang, Yao Rong, Yang Yang, Ming Chi, Zhen Liu, Yongmin Zhang, Peng Yu, Yuou Teng
Abstract
Compound<bold>5-61</bold>, a 5-(2-carboxyethenyl)isatin derivative was previously shown to have potent anticancer activity. Its effect on angiogenesis was further explored in this study.
Topics & Concepts
IsatinDerivative (finance)AngiogenesisChemistryCancer researchStereochemistryCombinatorial chemistryMedicineOrganic chemistryBusinessFinanceCancer Mechanisms and TherapyClick Chemistry and ApplicationsCancer therapeutics and mechanisms