Novel bifluorescent Zn(II)–cryptolepine–cyclen complexes trigger apoptosis induced by nuclear and mitochondrial DNA damage in cisplatin-resistant lung tumor cells
Zhenfeng Wang, Xiaofeng Zhou, Qiao-Chang Wei, Qi‐Pin Qin, Jinxian Li, Ming‐Xiong Tan, Shu‐Hua Zhang
Topics & Concepts
CyclenChemistryCisplatinMitochondrionApoptosisDNA damageCytotoxicityDNACytosolMolecular biologyBiochemistryIn vitroStereochemistryBiologyEnzymeChemotherapyGeneticsSynthesis and bioactivity of alkaloidsCell death mechanisms and regulationCancer therapeutics and mechanisms