Mechanistic and Structural Features of PROTAC Ternary Complexes
Ryan Casement, Adam G. Bond, Conner Craigon, Alessio Ciulli
Topics & Concepts
Ternary complexTernary operationChemistryUbiquitinCooperativityComputational biologyUbiquitin ligaseProtein degradationBiophysicsNanotechnologyComputer scienceBiochemistryBiologyMaterials scienceEnzymeProgramming languageGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis