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Submicrometer-Sized Roughness Suppresses Bacteria Adhesion

N. Encinas, Ching‐Yu Yang, Florian Geyer, Anke Kaltbeitzel, Philipp Baumli, Jonas Reinholz, Volker Mailänder, Hans‐Jürgen Butt, Doris Vollmer

2020ACS Applied Materials & Interfaces115 citationsDOIOpen Access PDF

Abstract

to surfaces of different topography and wettability over long exposure times (>7 days). Gram-negative and positive bacterial strains are tested for comparison. We show that an irregular three-dimensional layer of silicone nanofilaments suppresses bacterial adhesion, both in the presence and absence of an air cushion. We hypothesize that a 3D topography can delay biofilm formation (i) if bacteria do not fit into the pores of the coating or (ii) if bending of the bacteria is required to adhere. Thus, such a 3D topography offers an underestimated possibility to design antibacterial surfaces that do not require biocides or antibiotics.

Topics & Concepts

BiofilmBiofoulingAdhesionMaterials scienceWettingBacteriaBiocideSiliconeCoatingSurface roughnessPolymerNanotechnologySurface finishChemical engineeringComposite materialChemistryOrganic chemistryBiologyMembraneGeneticsBiochemistryEngineeringBacterial biofilms and quorum sensingAntimicrobial agents and applicationsPolymer Surface Interaction Studies
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