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Antibiotic resistance: bioinformatics-based understanding as a functional strategy for drug design

Umar Ndagi, Abubakar A. Falaki, Maryam Abdullahi, Monsurat M. Lawal, Mahmoud E. S. Soliman

2020RSC Advances71 citationsDOIOpen Access PDF

Abstract

study is well cemented and this facilitates the discovery of potent antibiotics. In this review, we seek to give an overview of earlier reviews and molecular and structural understanding of bacteria resistance to antibiotics, while focusing on the recent bioinformatics approach to antibacterial drug discovery.

Topics & Concepts

AntibioticsDrugDrug resistanceAntibiotic resistanceComputational biologyPharmacologyMedicineBioinformaticsComputer scienceChemistryBiologyMicrobiologyAntibiotic Resistance in BacteriaBacterial Identification and Susceptibility TestingBacteriophages and microbial interactions
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