Immune proteins C1q and CD47 may contribute to aberrant microglia-mediated synapse loss in the aging monkey brain that is associated with cognitive impairment
S DeVries, Bryce Conner, Christina Dimovasili, Tara L. Moore, Maria Medalla, Farzad Mortazavi, Douglas L. Rosene
Topics & Concepts
SynapseNeuroscienceMicrogliaBiologyDorsolateral prefrontal cortexCD47Synaptic pruningImmune systemPrefrontal cortexPsychologyCognitionInflammationImmunologyNeuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function StudiesAdenosine and Purinergic Signaling