The novel DYRK1A inhibitor KVN93 regulates cognitive function, amyloid-beta pathology, and neuroinflammation
Hyunju Lee, Hanwoong Woo, Ha-Eun Lee, Hyongjun Jeon, Ka‐Young Ryu, Jin Han Nam, Seong Gak Jeon, HyunHee Park, Ji-Soo Lee, Kyung‐Min Han, Sang Min Lee, Jeongyeon Kim, Jeongyeon Kim, Ri Jin Kang, Young‐Ho Lee, Jae‐Ick Kim, Jae‐Ick Kim, Hyang‐Sook Hoe
Topics & Concepts
NeuroinflammationDYRK1AAstrocyteAmyloid betaNeprilysinMicrogliaChemistryPharmacologyKinaseNeuroscienceMedicineBiologyInternal medicineInflammationCentral nervous systemEnzymeBiochemistryDiseaseAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders