Utility of Human-Derived Models for Glioblastoma
Xujun Luo, William A. Weiss
Abstract
Abstract Summary: In this issue, Pine and colleagues compared single-cell RNA-sequencing data across four distinct types of glioblastoma stem cell–derived tumor models, reinforcing the importance of a three-dimensional microenvironment for accurate recapitulation of cellular states. See related article by Pine et al., p. 964.
Topics & Concepts
GlioblastomaComputational biologyBiologyRNAComputer scienceEvolutionary biologyGeneticsCancer researchGeneSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsCell Image Analysis Techniques