The Na<sup>+</sup>-K<sup>+</sup>-ATPase is needed in glia of touch receptors for responses to touch in<i>C. elegans</i>
Christina K. Johnson, Jesús Fernandez-Abascal, Ying Wang, Lei Wang, Laura Bianchi
Abstract
Increasing evidences support that accessory cells in mechanosensors regulate neuronal output; however, the glial molecular mechanisms that control this regulation are not fully understood. We show here in Caenorhabditis elegans that specific glial Na + -K + -ATPase genes are needed for nose touch-avoidance behavior. Our data support the requirement of these Na + -K+-ATPases for homeostasis of Na + and K + in nose touch receptors. Our data add to our understanding of glial regulation of mechanosensors.
Topics & Concepts
Caenorhabditis elegansNeuroscienceCell biologyReceptorATPaseBiologyChemistryGeneBiochemistryEnzymeGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninNeurobiology and Insect Physiology Research