Protective effect of SIRT6 on cholesterol crystal-induced endothelial dysfunction via regulating ACE2 expression
Zihan Zheng, Bo Wang, Xiaohan Lv, Feng Yao, Hongqian Gao, Zhen Jin, Yizhen Liu, Ying Deng, Danli Chen, Xuan Ning, Weirong Wang, Jianyu He, Rong Lin
Topics & Concepts
Endothelial dysfunctionBiologySIRT6EnosTransfectionUmbilical veinTranscription factorEndotheliumGene knockdownNAD+ kinaseEndothelial activationNitric oxide synthaseSignal transductionCell biologyNitric oxideInflammationDownregulation and upregulationAngiotensin IIEnzymeBiochemistrySirtuinEndocrinologyImmunologyApoptosisGeneIn vitroReceptorSirtuins and Resveratrol in MedicineRNA regulation and diseaseCalpain Protease Function and Regulation