Litcius/Paper detail

Highly conserved brain vascular receptor ALPL mediates transport of engineered AAV vectors across the blood-brain barrier

Tyler C. Moyer, Brett Hoffman, Weitong Chen, Ishan Shah, Xiao‐Qin Ren, Tatiana M. Knox, Jiachen Liu, Wei Wang, Jiangyu Li, Hamza Khalid, Anupriya S. Kulkarni, Munachiso Egbuchulam, Joseph Clement, Alexis Bloedel, Matthew A. Child, Rupinderjit Kaur, Emily Rouse, Kristin Graham, Damien Maura, Zachary Thorpe, Ambreen Sayed-Zahid, Charlotte Hiu-Yan Chung, A. V. Kutchin, Amy J. Johnson, Johnny Yao, Jeffrey S. Thompson, Nilesh Pande, Mathieu Nonnenmacher

2025Molecular Therapy33 citationsDOIOpen Access PDF

Topics & Concepts

Blood–brain barrierCell biologyBiologyReceptorNeuroscienceCentral nervous systemGeneticsAdenosine and Purinergic SignalingVirus-based gene therapy researchComplement system in diseases
Highly conserved brain vascular receptor ALPL mediates transport of engineered AAV vectors across the blood-brain barrier | Litcius