Litcius/Paper detail

FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity

Hilde Herrema, Dongxian Guan, Jae Won Choi, Xudong Feng, Mario Andrés Salazar Hernández, Farhana Faruk, Thomas Auen, Eliza Boudett, Rongya Tao, Hyonho Chun, Umut Özcan

2022Cell Metabolism39 citationsDOIOpen Access PDF

Topics & Concepts

Unfolded protein responseEndoplasmic reticulumHomeostasisGlucose homeostasisSignal transductionATF4Type 2 diabetesBiologyCell biologyObesityEndocrinologyDiabetes mellitusInternal medicineMedicineInsulin resistanceEndoplasmic Reticulum Stress and DiseasePancreatic function and diabetesGenomics, phytochemicals, and oxidative stress