A Conserved Machinery Underlies the Synthesis of a Chitosan Layer in the <i>Candida</i> Chlamydospore Cell Wall
Leo D. Bemena, Kyunghun Min, James B. Konopka, Aaron M. Neiman
Abstract
The cell wall is the interface between the fungal cell and its environment and disruption of cell wall assembly is an effective strategy for antifungal therapies. Therefore, a detailed understanding of how cell walls form is critical to identify potential drug targets and develop therapeutic strategies.
Topics & Concepts
Cell wallAntifungalChitosanCellChlamydosporeBiologyCell biologyComputational biologyMicrobiologyBiochemistrySporeAntifungal resistance and susceptibilityFungal Infections and StudiesCarbohydrate Chemistry and Synthesis