Boron tribromide as a reagent for anti-Markovnikov addition of HBr to cyclopropanes
Matthew H. Gieuw, Shuming Chen, Zhihai Ke, K. N. Houk, Ying‐Yeung Yeung
Abstract
Anti-Markovnikov hydrobromination of cyclopropanes was achieved using boron tribromide and water as the bromine and proton sources, respectively.
Topics & Concepts
Markovnikov's ruleTribromideChemistryBromineReagentBoronOrganic chemistryMedicinal chemistryRegioselectivityCatalysisCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsCatalytic Alkyne Reactions