Cytotoxic effects of NIR responsive chitosan-polymersome layer coated melatonin-upconversion nanoparticles on HGC27 and AGS gastric cancer cells: Role of the ROS/PI3K/Akt/mTOR signaling pathway
Zhiyuan Fan, Yuheng Shao, Xiao Jiang, Jinglan Zhou, Liang Yang, Haitao Chen, Wentao Liu
Topics & Concepts
PI3K/AKT/mTOR pathwayPolymersomeChemistryCytotoxic T cellCancer cellChitosanNanoparticleCancerProtein kinase BMelatoninCell biologyApoptosisCancer researchBiophysicsNanotechnologyBiochemistryMaterials scienceBiologyMedicineIn vitroInternal medicineNeuroscienceOrganic chemistryCopolymerPolymerAmphiphileNanoplatforms for cancer theranosticsSulfur Compounds in BiologyCircadian rhythm and melatonin